American Journal of Epidemiology Vol. 122, No. 4: 644-656
Copyright © 1985 by The Johns Hopkins University School of Hygiene and Public Health
research-article |
FRAMINGHAM DISABILITY STUDY: RELATIONSHIP OF DISABILITY TO CARDIOVASCULAR RISK FACTORS AMONG PERSONS FREE OF DIAGNOSED CARDIOVASCULAR DISEASE
1Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute Bethesda, MD
2Department of Social Medicine and Health Policy, Harvard Medical School Boston, MA
3MGH Institute of Health Professionals, Massachusetts General Hospital Boston, MA
4National Center for Health Statistics Hyattsville, MD
5Epidemiology, Demography, and Biometry Program, National Institute on Aging Bethesda, MD
Reprint requests to Joan L. Pinsky, National Heart, Lung, and Blood Institute, Federal Building, Room 2C08, Bethesda, MD 20205
The relationship between physical disability and cardiovascular risk factors among persons free of diagnosed cardiovascular disease was examined. Between 1948 and 1951, a cohort of adult, Framingham, Massachusetts, residents was assembled for a longitudinal examination of cardiovascular disease. Twenty-seven years after the participants' initial examination (between 1976 and 1978), members of the cohort who were still participating in the Framingham Heart Study were interviewed to ascertain their self-assessed ability to perform various physical activities. A score on the cumulative disability index was assigned to 2,021 persons free of diagnosed cardiovascular disease. Analyses controlled for noncardiovascular health conditions which were identified as related to disability. Among women, both long-term and current hypertension and body mass index, as well as diabetes, were associated with disability. Among men, long-term hypertension was related to disability. Age-specific analyses indicated that, for women, current hypertension was statistically significantly related to disability in the middle and oldest age groups; long-term hypertension was related to disability in the middle age group. Both long-term and current measures of diabetes in the oldest age group and long-term measure of cigarette use in the middle age group of women were also related to disability. Age-specific analyses among men indicated that the only statistically significant risk factor was long-term hypertension in the youngest age group. Cholesterol was not related to disability. Results suggest that certain cardiovascular risk factors should be considered in efforts to understand further the development of disability.
cardiovascular diseases; disability; physical; risk
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  M. F. Elias and P. K. Elias Blood Pressure and Disability: Novus Orsa Hypertension, December 1, 2007; 50(6): 1006 - 1008. [Full Text] [PDF]
|
|
|
|
|
|
I. Hajjar, D. T. Lackland, L. A. Cupples, and L. A. Lipsitz Association Between Concurrent and Remote Blood Pressure and Disability in Older Adults Hypertension, December 1, 2007; 50(6): 1026 - 1032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Stenholm, P. Sainio, T. Rantanen, S. Koskinen, A. Jula, M. Heliovaara, and A. Aromaa High Body Mass Index and Physical Impairments as Predictors of Walking Limitation 22 Years Later in Adult Finns J. Gerontol. A Biol. Sci. Med. Sci., August 1, 2007; 62(8): 859 - 865. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K. Figaro, S. B. Kritchevsky, H. E. Resnick, R. I. Shorr, J. Butler, A. Shintani, B. W. Penninx, E. M. Simonsick, B. H. Goodpaster, A. B. Newman, et al. Diabetes, Inflammation, and Functional Decline in Older Adults: Findings from the Health, Aging and Body Composition (ABC) study. Diabetes Care, September 1, 2006; 29(9): 2039 - 2045. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. C. Reid, C. S. Williams, and T. M. Gill Back Pain and Decline in Lower Extremity Physical Function Among Community-Dwelling Older Persons J. Gerontol. A Biol. Sci. Med. Sci., June 1, 2005; 60(6): 793 - 797. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. E. Furner, B. E. Giloth, L. Arguelles, T. P. Miles, and J. H. Goldberg A Co-Twin Control Study of Physical Function in Elderly African American Women J Aging Health, February 1, 2004; 16(1): 28 - 43. [Abstract] [PDF]
|
|
|
|
 |
|
 M. L. Daviglus, K. Liu, A. Pirzada, L. L. Yan, D. B. Garside, J. Feinglass, J. M. Guralnik, P. Greenland, and J. Stamler Favorable Cardiovascular Risk Profile in Middle Age and Health-Related Quality of Life in Older Age Arch Intern Med, November 10, 2003; 163(20): 2460 - 2468. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Chen, O. I. Bermudez, and K. L. Tucker Waist Circumference and Weight Change Are Associated With Disability Among Elderly Hispanics J. Gerontol. A Biol. Sci. Med. Sci., January 1, 2002; 57(1): M19 - 25. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. B. Ford, M. R. Haug, K. C. Stange, A. D. Gaines, L. S. Noelker, and P. K. Jones Sustained Personal Autonomy: A Measure of Successful Aging J Aging Health, November 1, 2000; 12(4): 470 - 489. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Ebrahim, S G. Wannamethee, P. Whincup, M. Walker, and A G. Shaper Locomotor disability in a cohort of British men: the impact of lifestyle and disease Int. J. Epidemiol., June 1, 2000; 29(3): 478 - 486. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. G. Parker, M. Thorslund, O. Lundberg, and I. Kareholt Predictors of Physical Function among the Oldest Old: A Comparison of Three Outcome Variables in a 24-Year Follow-Up J Aging Health, August 1, 1996; 8(3): 444 - 460. [Abstract] [PDF]
|
|
|
|
 |
|
 L. J. Launer, T. Harris, C. Rumpel, and J. Madans Body Mass Index, Weight Change, and Risk of Mobility Disability in Middle-aged and Older Women: The Epidemiologic Follow-up Study of NHANES I JAMA, April 13, 1994; 271(14): 1093 - 1098. [Abstract] [PDF]
|
|
|
|
|
|
E. M. Crimmins and Y. Saito Getting Better and Getting Worse: Transitions in Functional Status among Older Americans J Aging Health, February 1, 1993; 5(1): 3 - 36. [Abstract] [PDF]
|
|
|
|
|
|
L. P. Fried, S. J. Herdman, K. E. Kuhn, G. Rubin, and K. Turano Preclinical Disability: Hypotheses About the Bottom of the Iceberg J Aging Health, May 1, 1991; 3(2): 285 - 300. [Abstract] [PDF]
|
|