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American Journal of Epidemiology Vol. 122, No. 2: 323-334
Copyright © 1985 by The Johns Hopkins University School of Hygiene and Public Health


research-article

THE STANFORD FIVE-CITY PROJECT: DESIGN AND METHODS

JOHN W. FARQUHAR1, STEPHEN P. FORTMANN1, NATHAN MACCOBY1, WILLIAM L. HASKELL1, PAUL T. WILLIAMS1, JUNE A. FLORA1, C. BARR TAYLOR1, BYRON W. BROWN, JR.1, DOUGLAS S. SOLOMON2 and STEPHEN B. HULLEY3

1Stanford Center for Research in Disease Prevention, Stanford University School of Medicine Stanford, CA 94305
2Apple Computer, Inc. Cupertino, CA
3Department of Epidemiology and International Health, School of Medicine, University of California San Francisco, CA

Reprint requests to Dr. John W. Farquhar

The Stanford Five-City Project is a large experimental field study of community health education for the prevention of cardiovascular disease. It will provide data on fundamental questions in cardiovascular disease epidemiology, communication, health education, behavior change, and community organization, and will also test the ability of a potentially cost-effective program to prevent cardiovascular disease at the community level. This paper describes the purposes, hypotheses, design, and methods of the Five-City Project as a reference for future papers describing results. It is hypothesized that a 20% decrease in cardiovascular disease risk will lead to a significant decline in cardiovascular disease event rates in two treatment communities compared with three reference communities as a result of a six-year intervention program of community-wide health education and organization. Risk factor change will be assessed through four surveys of independent samples and in a repeatedly surveyed cohort Cardiovascular disease event rates will be assessed through continous community surveillance of fatal and nonfatal myocardial infarction and stroke.

cardiovascular diseases; health education; primary prevention; survey methods


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