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American Journal of Epidemiology Vol. 114, No. 1: 149-154
Copyright © 1981 by The Johns Hopkins University School of Hygiene and Public Health

research-article

A MULTIVARIATE ANALYSIS OF FAMILY DATA

ALLAN DONNER1,  and JOHN J. KOVAL2

1Department of Epidemiology and Biostatistics, The University of Western Ontario London, Ontario, Canada, N6A 5B7
2Department of Statistical and Actuarial Sciences, The University of Western Ontario London, Ontario

Reprint requests to Dr. Donner at this address

The authors describe the application of multivariate analysis to the problem of estimating intra-family correlations and testing them for statistical significance. This is illustrated by a re-analysis of survey data collected by Miall and Oldham (Clin Sci 1958;17:459-87) on the familial aggregation of blood pressure. The multivariate analysis provides collective tests of significance for parent-child and child-child correlations based on likelihood ratio theory, and maximum likelihood estimates for individual intra-family correlations.

family characteristics; multivariate analysis

Dr. Donner's work was supported by a National Health and Welfare Research Scholarship (Canada), and Mr. Koval's work by the Natural Science and Engineering Research Council


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