American Journal of Epidemiology Vol. 113, No. 4: 357-370
Copyright © 1981 by The Johns Hopkins University School of Hygiene and Public Health
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RISK FACTORS FOR FATAL HEART ATTACK IN YOUNG WOMEN
1The George Washington University Biostatistics Center 7979 Old Georgetown Road, Bethesda, MD 20014
2The George Washington University Medical Center, Department of Pathology Washington, DC
3Loma Linda University, Department of Biostatistics and Epidemiology Loma Linda, CA
4Interinstitutional Cardiovascular Center, Chicago Heart Association Chicago, IL
5Wayne State University, Department of Community Medicine Detroit, MI
6The George Washington University Medical Center, Department of Medicine Washington, DC
7Rush-Presbyterian-St. Luke's Medical Center, Department of Preventive Medicine Chicago, IL
8New York Medical College, Department of Community and Preventive Medicine New York, NY
9National Institute of Child Health and Human Development, Contraceptive Evaluation Branch Bethesda, MD
10University of Pennsylvania Medical School, Department of Medicine Philadelphia, PA
reprint requests to Dean E. Krueger
Krueger, D. E. (The George Washington U. Blostatlstlcs Center, 7979 Old Georgetown Road, Bethesda, MD 20014), S. S. Ellenberg, S. Bloom, B. M. Calkins, R. Jacyna, D. C. Nolan, R. Phillips, J. C. Rlos, R. Sobleski, R. B. Shekelle, K. M. Spector, B. V. Stadel, P. D. Stolley and M. Terris. Risk factors for fatal heart attack in young women. Am J Epidemiol 1981;113:357–70.
Deaths of 338 women at ages 15–44 years attributed to myocardial infarction (Ml) on death certificates during an 18-month period in five metropollitan areas were investigated. Evidence of recent Ml or evidence that death occurred suddenly was obtained for about half (163) from records of hospitals or medical examiners or from relatives. A case-control study (involving one deceased control, and one hospitalized living control) of risk factors for heart attack was then conducted using interviews with relatives and abstracts of records of hospitals and physicians identified by the relatives as sources of medical care. information was obtained on history of prior Ml, other heart disease, diabetes, thromboembolism, stroke, hypertension, high cholesterol, obesity, oophorectomy, oral contraception and cigarette smoking. Data are presented on the prevalence of these potential risk factors for the case group and each control group, and for subsets of cases consisting of those without prior heart disease, definite Ml only, sudden death only, and white women only. Multivariate analyses identify somewhat different sets of risk factors and different levels of risk for the various subgroups. In general, the risk factors are those that have been reported for men, despite the major difference in level of mortality.
myocardial infarction; retrospective studies
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