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American Journal of Epidemiology Vol. 112, No. 3: 409-416
Copyright © 1980 by The Johns Hopkins University School of Hygiene and Public Health

other

PREVENTION FOR MULTIFACTORIAL DISEASES

STEPHEN D. WALTER

Dept. of Epidemiology and Public Health, Yale U. School of Medicine 60 College St., New Haven, CT 06510

address for reprints.

This paper addresses the question of choosing between alternative preventive strategies for diseases with several risk factors. Estimates are obtained of the reduction in cases to be anticipated following a modification of the population exposure to one or several of these hazards. In practice, such estimates must often be made without knowledge of the joint distribution of exposure to risk, and so general conditions are established under which the factor attributable risks, calculated by ignoring all other factors, are unbiased effect measures. These concepts are illustrated by data from several epidemiologic studies.

biometry; epidemiologic methods; prevention


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