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American Journal of Epidemiology Vol. 110, No. 4: 479-491
Copyright © 1979 by The Johns Hopkins University School of Hygiene and Public Health

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FAMILIAL AGGREGATION OF BLOOD PRESSURE AND WEIGHT IN ADOPTIVE FAMILIES

I. COMPARISONS OF BLOOD PRESSURE AND WEIGHT STATISTICS AMONG FAMILIES WITH ADOPTED, NATURAL, OR BOTH NATURAL AND ADOPTED CHILDREN

JOSEPH L. ANNEST1, CHARLES F. SING2,, PIERRE BIRON3 and JEAN-GUY MONGEAU4

1National Center for Health Statistics, Health Examination Statistics Division Hyattsville, MD
2Department of Human Genetics, 1137 E. Catherine St., University of Michigan Ann Arbor, MI 48109
3Department of Pharmacology, University of Montreal Montreal, Quebec
4Hôpital Ste Justine, 3175 Cote Ste Catherine Montreal, Quebec

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Tests of homogeneity of means, variances and correlations for systolic blood pressure (BP), diastolic BP and weight among subdivisions of a sample of adoptive families are presented. The means and variances of either type of BP, but not weight, were not significantly heterogeneous among families grouped according to the number of parents and children, natural and/or adopted, in the family unit. Estimates of correlation between family members were not heterogeneous among subdivisions for each of the three variables. Our results indicate that these data are suitable for a genetic analysis of familial aggregation. Pooled correlations suggest that the degree of resemblance of BP and of weight between family members varies within and across generations. Correlations involving the adoptees were significantly different from zero only for diastolic BP.

adolescence; blood pressure; body weight; family characteristics


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