American Journal of Epidemiology Vol. 107, No. 6: 545-551
Copyright © 1978 by The Johns Hopkins University School of Hygiene and Public Health
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THE REAPPEARANCE OF A CLASSICAL EPIDEMIC OF INFECTIOUS HEPATITIS IN WORCESTER, MASSACHUSETTS
1 Life Sciences Department, Worcester Polytechnic Institute Worcester, MA 01609
2 Department of Family and Community Medicine, University of Massachusetts School of Medicine Worcester, MA 01605
3 Division of Microbiology, Biology Department, Clark University Worcester, MA 01610
4 Director of Laboratories, Department of Public Health Worcester, MA 01605
5 Assistant Director of Environmental Health, Department of Public Health Worcester
6 Mechanical Engineering Department, Worcester Polytechnic Institute
Worcester, MA, experienced an outbreak of hepatitis during 19691970, an expected event which had occurred previously at eight-year intervals since reporting of the disease began In 1950. Other Massachusetts communities of similar character and the nation did not experience an epidemic during that same period. An extensive epidemiologic study of the disease illustrated that the epidemic followed the classical pattern in which Individuals 514 years old were most affected Irrespective of sex. During the interepidemlc years from 19681972 in Worcester, and in all years (19681972) In both New Bedford, and Springfield, MA, those primarily affected were young adults 1530 years old, with male cases predominating. Soclodemographic statistical analyses also Indicated the classical pattern of the less affluent, less educated, and sometimes the more crowded populations being at greater risk of contracting the disease. This outbreak of hepatitis was comparable to another In Greenland two years later in which Immunologic methods differentiated between type A and type B viral infections. The data from both studies support the conclusion that the type B virus, often associated with parenteral drug use, is the predominate Infectious agent during the Interepidemic (endemic) periods. The type A virus is most likely responsible for the periodic epidemics.
hepatitis; outbreaks; socioeconomic factors