American Journal of Epidemiology Vol. 107, No. 6: 499-509
Copyright © 1978 by The Johns Hopkins University School of Hygiene and Public Health
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A STUDY OF DIET AND BREAST CANCER1
2 Epidemiology Unit, National Cancer Institute of Canada
3 University of Sherbrooke
4 University of Manitoba
5 University of Saskatchewan
6 University of Toronto
Reprint requests to Dr. Miller, NCIC Epidemiology Unit, University of Toronto, McMurrich Building, Toronto, Ontario M5S 1A8, Canada.
A case-control study has been conducted in four areas in Canada In which 400 cases of breast cancer matched by age and marital status with neighborhood controls were administered a medical and dietary history questionnaire, a 24-hour recall for dietary information and a four-day diet record. The Study has produced evidence of an association between an Increased Intake of nutrients, especially total fat, in both pre-menopausal and post-menopausal women with breast cancer. Reasons why a weak association might have been anticipated are discussed, and It Is concluded that In reality the association is stronger. Furthermore, Its consistency with other evidence, both experimental and international, suggests that it Is causal.
breast neoplasms; cancer; diet; nutrition
1 This study was supported by the National Cancer Institute of Canada and in part under National Health Research and Development Project No. 613-1047-30 of the Department of National Health and Welfare of Canada.
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