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American Journal of Epidemiology Vol. 104, No. 6: 609-620
Copyright © 1976 by The Johns Hopkins University School of Hygiene and Public Health


research-article

STRATIFICATION BY A MULTIVARIATE CONFOUNDER SCORE

OLLI S. MIETTINEN1

1Departments of Epidemiology and Biostatistics, Harvard School of Public Health, and Department of Cardiology, Children's Hospital Medical Center Boston, MA 02115

The complexity and inefficiency of multiple cross-classification as a means of controlling confounding in etiologic research may be avoided upon summarizing the pattern of confounding factors for each subject in terms of a multivariate score. The control of confounding may be based on stratification by the score, with stratum-specific contingency tables obtained and analyzed in the usual manner.

epidemiologic methods; biometry


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